EC number:6.2.1.47

Enzyme

Download
EC Tree
     6. Ligases
        6.2 Forming carbon-sulfur bonds
            6.2.1 Acid-thiol ligases
ID:6.2.1.47
Description:Medium-chain-fatty-acid--(acyl-carrier-protein) ligase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.2.1.47
BRENDA Enzyme Link: BRENDA 6.2.1.47
KEGG Enzyme Link: KEGG6.2.1.47
BioCyc Enzyme Link: BioCyc 6.2.1.47
ExPASy Enzyme Link: ExPASy6.2.1.47
EC2PDB Enzyme Link: EC2PDB 6.2.1.47
ExplorEnz Enzyme Link: ExplorEnz 6.2.1.47
PRIAM enzyme-specific profiles Link: PRIAM 6.2.1.47
IntEnz Enzyme Link: IntEnz 6.2.1.47
MEDLINE Enzyme Link: MEDLINE 6.2.1.47

EC number:6.2.1.47

MSA:

6.2.1.47;
Phylogenetic Tree:

6.2.1.47;
Uniprot:
M-CSA:
RHEA:50460 a medium chain fatty acid + ATP + holo-[ACP] = a medium-chain fatty acyl-[ACP] + AMP + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4].[*:5]-[O;H0;+0:6]-[P;H0;+0:7](-[*:8])(=[*:9])-[*:10].[*:11]-[SH;+0:12]>>[*:5]-[OH;+0:6].[*:8]-[P;H0;+0:7](=[*:9])(-[*:10])-[OH;+0:4].[*:11]-[S;H0;+0:12]-[C;H0;+0:2](-[*:1])=[*:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
De novo biosynthesis of terminal alkyne-labeled natural products.Zhu X, Liu J, Zhang W2015 Feb25531891
Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula.Edwards DJ, Marquez BL, Nogle LM, McPhail K, Goeger DE, Roberts MA, Gerwick WH2004 Jun15217615