Enzyme

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ID:6.2.1.n3
Description:Malonate--CoA ligase.

3D structure

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References

RHEA:32139 ATP + CoA + malonate = AMP + diphosphate + malonyl-CoA
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4].[*:5]-[P;H0;+0:6](=[*:7])(-[*:8])-[O;H0;+0:9]-[*:10].[*:11]-[SH;+0:12]>>[*:10]-[OH;+0:9].[*:5]-[P;H0;+0:6](=[*:7])(-[*:8])-[OH;+0:4].[*:11]-[S;H0;+0:12]-[C;H0;+0:2](-[*:1])=[*:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesis.Witkowski A, Thweatt J, Smith S2011 Sep 3021846720
Malonyl-CoA synthetase, encoded by ACYL ACTIVATING ENZYME13, is essential for growth and development of Arabidopsis.Chen H, Kim HU, Weng H, Browse J2011 Jun21642549