EC number:6.3.1.10
Enzyme
Download| EC Tree |
| 6. Ligases |
| 6.3 Forming carbon-nitrogen bonds |
| 6.3.1 Acid-D-ammonia (or amine) ligases (amide synthases) |
| ID: | 6.3.1.10 |
|---|---|
| Description: | Adenosylcobinamide-phosphate synthase. |
| Cath: | 3.40.640.10; 3.90.1150.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.3.1.10 |
| BRENDA Enzyme Link: | BRENDA 6.3.1.10 |
| KEGG Enzyme Link: | KEGG6.3.1.10 |
| BioCyc Enzyme Link: | BioCyc 6.3.1.10 |
| ExPASy Enzyme Link: | ExPASy6.3.1.10 |
| EC2PDB Enzyme Link: | EC2PDB 6.3.1.10 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.3.1.10 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.3.1.10 |
| IntEnz Enzyme Link: | IntEnz 6.3.1.10 |
| MEDLINE Enzyme Link: | MEDLINE 6.3.1.10 |
| RHEA:21896 | (R)-1-aminopropan-2-yl phosphate + adenosylcob(III)yrate + ATP = adenosylcob(III)inamide phosphate + ADP + H(+) + phosphate |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[OH;+0:6].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[O;H0;+0:11]-[*:12]>>[*:1]-[NH;+0:2]-[C;H0;+0:4](=[*:3])-[*:5].[*:12]-[OH;+0:11].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The biosynthesis of adenosylcobalamin (vitamin B12). | Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC | 2002 Aug | 12195810 |
| Three-dimensional structure of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica. | Cheong CG, Bauer CB, Brushaber KR, Escalante-Semerena JC, Rayment I | 2002 Apr 16 | 11939774 |
| RHEA:12572 | (R)-1-aminopropan-2-ol + adenosylcob(III)yrate + ATP = adenosylcob(III)inamide + ADP + H(+) + phosphate |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[OH;+0:6].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[O;H0;+0:11]-[*:12]>>[*:1]-[NH;+0:2]-[C;H0;+0:4](=[*:3])-[*:5].[*:12]-[OH;+0:11].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The biosynthesis of adenosylcobalamin (vitamin B12). | Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC | 2002 Aug | 12195810 |
| Three-dimensional structure of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica. | Cheong CG, Bauer CB, Brushaber KR, Escalante-Semerena JC, Rayment I | 2002 Apr 16 | 11939774 |