Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.1 Acid-D-ammonia (or amine) ligases (amide synthases)
ID:6.3.1.6
Description:Glutamate--ethylamine ligase.
Alternative Name: Theanine synthetase.
N(5)-ethyl-L-glutamine synthetase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.1.6
BRENDA Enzyme Link: BRENDA 6.3.1.6
KEGG Enzyme Link: KEGG6.3.1.6
BioCyc Enzyme Link: BioCyc 6.3.1.6
ExPASy Enzyme Link: ExPASy6.3.1.6
EC2PDB Enzyme Link: EC2PDB 6.3.1.6
ExplorEnz Enzyme Link: ExplorEnz 6.3.1.6
PRIAM enzyme-specific profiles Link: PRIAM 6.3.1.6
IntEnz Enzyme Link: IntEnz 6.3.1.6
MEDLINE Enzyme Link: MEDLINE 6.3.1.6
MSA:

6.3.1.6;

Phylogenetic Tree:

6.3.1.6;

Uniprot:
M-CSA:
RHEA:20525 ATP + ethylamine + L-glutamate = ADP + H(+) + N(5)-ethyl-L-glutamine + phosphate
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[OH;+0:6].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[O;H0;+0:11]-[*:12]>>[*:12]-[OH;+0:11].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Cloning and expression of Methylovorus mays No. 9 gene encoding gamma-glutamylmethylamide synthetase: an enzyme usable in theanine formation by coupling with the alcoholic fermentation system of baker's yeast.Yamamoto S, Wakayama M, Tachiki T2008 Jan18175924
Characterization of theanine-forming enzyme from Methylovorus mays no. 9 in respect to utilization of theanine production.Yamamoto S, Wakayama M, Tachiki T2007 Feb17284842