EC number:6.3.2.24

Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.2 Acid-D-amino-acid ligases (peptide synthases)
ID:6.3.2.24
Description:Tyrosine--arginine ligase.
Alternative Name: Tyrosyl-arginine synthase.
Kyotorphin-synthesizing enzyme.
Kyotorphin synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.2.24
BRENDA Enzyme Link: BRENDA 6.3.2.24
KEGG Enzyme Link: KEGG6.3.2.24
BioCyc Enzyme Link: BioCyc 6.3.2.24
ExPASy Enzyme Link: ExPASy6.3.2.24
EC2PDB Enzyme Link: EC2PDB 6.3.2.24
ExplorEnz Enzyme Link: ExplorEnz 6.3.2.24
PRIAM enzyme-specific profiles Link: PRIAM 6.3.2.24
IntEnz Enzyme Link: IntEnz 6.3.2.24
MEDLINE Enzyme Link: MEDLINE 6.3.2.24

EC number:6.3.2.24

MSA:

6.3.2.24;
Phylogenetic Tree:

6.3.2.24;
Uniprot:
M-CSA:
RHEA:15345 ATP + L-arginine + L-tyrosine = AMP + diphosphate + H(+) + L-tyrosyl-L-arginine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[O;H0;+0:4]-[P;H0;+0:5](-[*:6])(=[*:7])-[*:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:3]-[OH;+0:4].[*:6]-[P;H0;+0:5](=[*:7])(-[*:8])-[OH;+0:12].[*:9]=[C;H0;+0:10](-[*:11])-[NH;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Kyotorphin (tyrosine-arginine) synthetase in rat brain synaptosomes.Ueda H, Yoshihara Y, Fukushima N, Shiomi H, Nakamura A, Takagi H1987 Jun 153597366