Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.2 Acid-D-amino-acid ligases (peptide synthases)
ID:6.3.2.30
Description:Cyanophycin synthase (L-arginine-adding).
Alternative Name: Multi-L-arginyl-poly-L-aspartate synthase.
Cyanophycin synthetase.
Prosite: PDOC50975;
PDB:
PDBScop

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.2.30
BRENDA Enzyme Link: BRENDA 6.3.2.30
KEGG Enzyme Link: KEGG6.3.2.30
BioCyc Enzyme Link: BioCyc 6.3.2.30
ExPASy Enzyme Link: ExPASy6.3.2.30
EC2PDB Enzyme Link: EC2PDB 6.3.2.30
ExplorEnz Enzyme Link: ExplorEnz 6.3.2.30
PRIAM enzyme-specific profiles Link: PRIAM 6.3.2.30
IntEnz Enzyme Link: IntEnz 6.3.2.30
MEDLINE Enzyme Link: MEDLINE 6.3.2.30
MSA:

6.3.2.30;

Phylogenetic Tree:

6.3.2.30;

Uniprot:
M-CSA:
RHEA:23888 [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ATP + L-arginine = [L-4-(L-arginin-2-N-yl)aspartate](n+1) + ADP + H(+) + phosphate
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[O;H0;+0:4]-[P;H0;+0:5](-[*:6])(=[*:7])-[*:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:3]-[OH;+0:4].[*:6]-[P;H0;+0:5](=[*:7])(-[*:8])-[OH;+0:12].[*:9]=[C;H0;+0:10](-[*:11])-[NH;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Molecular characterization of cyanophycin synthetase, the enzyme catalyzing the biosynthesis of the cyanobacterial reserve material multi-L-arginyl-poly-L-aspartate (cyanophycin).Ziegler K, Diener A, Herpin C, Richter R, Deutzmann R, Lockau W1998 May 159652408
Cyanophycin granule polypeptide formation and degradation in the cyanobacterium Aphanocapsa 6308.Allen MM, Hutchison F, Weathers PJ1980 Feb6767688
Cyanophycin synthetase-like enzymes of non-cyanobacterial eubacteria: characterization of the polymer produced by a recombinant synthetase of Desulfitobacterium hafniense.Ziegler K, Deutzmann R, Lockau W2002 May-Jun12132696
Purification of Synechocystis sp. strain PCC6308 cyanophycin synthetase and its characterization with respect to substrate and primer specificity.Aboulmagd E, Oppermann-Sanio FB, Steinbüchel A2001 May11319097
Molecular characterization of the cyanophycin synthetase from Synechocystis sp. strain PCC6308.Aboulmagd E, Oppermann-Sanio FB, Steinbüchel A2000 Nov11131019
Biosynthesis of the cyanobacterial reserve polymer multi-L-arginyl-poly-L-aspartic acid (cyanophycin): mechanism of the cyanophycin synthetase reaction studied with synthetic primers.Berg H, Ziegler K, Piotukh K, Baier K, Lockau W, Volkmer-Engert R2000 Sep10951215