EC number:6.3.2.32

Enzyme

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EC Tree
     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.2 Acid-D-amino-acid ligases (peptide synthases)
ID:6.3.2.32
Description:Coenzyme gamma-F420-2:alpha-L-glutamate ligase.
Prosite: PDOC50975;
PDB:
PDBScop

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.2.32
BRENDA Enzyme Link: BRENDA 6.3.2.32
KEGG Enzyme Link: KEGG6.3.2.32
BioCyc Enzyme Link: BioCyc 6.3.2.32
ExPASy Enzyme Link: ExPASy6.3.2.32
EC2PDB Enzyme Link: EC2PDB 6.3.2.32
ExplorEnz Enzyme Link: ExplorEnz 6.3.2.32
PRIAM enzyme-specific profiles Link: PRIAM 6.3.2.32
IntEnz Enzyme Link: IntEnz 6.3.2.32
MEDLINE Enzyme Link: MEDLINE 6.3.2.32

EC number:6.3.2.32

MSA:

6.3.2.32;
Phylogenetic Tree:

6.3.2.32;
Uniprot:
M-CSA:
RHEA:42332 ATP + L-glutamate + oxidized coenzyme F420-2 = ADP + H(+) + oxidized coenzyme alpha-F420-3 + phosphate
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[OH;+0:6].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[O;H0;+0:11]-[*:12]>>[*:12]-[OH;+0:11].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
CofE catalyzes the addition of two glutamates to F420-0 in F420 coenzyme biosynthesis in Methanococcus jannaschii.Li H, Graupner M, Xu H, White RH2003 Aug 1912911320
Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.Li H, Xu H, Graham DE, White RH2003 Aug 1912909715