EC number:6.3.2.36

Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.2 Acid-D-amino-acid ligases (peptide synthases)
ID:6.3.2.36
Description:4-phosphopantoate--beta-alanine ligase.
Alternative Name: Phosphopantothenate synthetase.
Cath: 3.40.50.12640;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.2.36
BRENDA Enzyme Link: BRENDA 6.3.2.36
KEGG Enzyme Link: KEGG6.3.2.36
BioCyc Enzyme Link: BioCyc 6.3.2.36
ExPASy Enzyme Link: ExPASy6.3.2.36
EC2PDB Enzyme Link: EC2PDB 6.3.2.36
ExplorEnz Enzyme Link: ExplorEnz 6.3.2.36
PRIAM enzyme-specific profiles Link: PRIAM 6.3.2.36
IntEnz Enzyme Link: IntEnz 6.3.2.36
MEDLINE Enzyme Link: MEDLINE 6.3.2.36

EC number:6.3.2.36

MSA:

6.3.2.36;
Phylogenetic Tree:

6.3.2.36;
Uniprot:
M-CSA:
RHEA:27930 (R)-4-phosphopantoate + ATP + beta-alanine = (R)-4'-phosphopantothenate + AMP + diphosphate + H(+)
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[O;H0;+0:4]-[P;H0;+0:5](-[*:6])(=[*:7])-[*:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:3]-[OH;+0:4].[*:6]-[P;H0;+0:5](=[*:7])(-[*:8])-[OH;+0:12].[*:9]=[C;H0;+0:10](-[*:11])-[NH;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Pantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea.Yokooji Y, Tomita H, Atomi H, Imanaka T2009 Oct 919666462