EC number:6.3.2.4

Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.2 Acid-D-amino-acid ligases (peptide synthases)
ID:6.3.2.4
Description:D-alanine--D-alanine ligase.
Alternative Name: D-alanylalanine synthetase.
D-alanyl-D-alanine synthetase.
D-Ala-D-Ala synthetase.
Alanylalanine synthetase.
Alanine:alanine ligase (ADP-forming).
Prosite: PDOC50975; PDOC00659;
PDB:
PDBScop
1EHI 8024142; 8031856; 8036521; 8044234; 8024142; 8031856; 8036521; 8044234;
4C5C 8024137; 8031855; 8036516; 8044233; 8024137; 8031855; 8036516; 8044233;
4C5B 8024137; 8031855; 8036516; 8044233; 8024137; 8031855; 8036516; 8044233;
4C5A 8024137; 8031855; 8036516; 8044233; 8024137; 8031855; 8036516; 8044233;
2DLN 8024137; 8031855; 8036516; 8044233;
 » show all
Cath: 3.30.1490.20; 3.30.470.20; 3.40.1190.10; 3.40.1390.10; 3.90.190.20; 3.40.50.20;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.2.4
BRENDA Enzyme Link: BRENDA 6.3.2.4
KEGG Enzyme Link: KEGG6.3.2.4
BioCyc Enzyme Link: BioCyc 6.3.2.4
ExPASy Enzyme Link: ExPASy6.3.2.4
EC2PDB Enzyme Link: EC2PDB 6.3.2.4
ExplorEnz Enzyme Link: ExplorEnz 6.3.2.4
PRIAM enzyme-specific profiles Link: PRIAM 6.3.2.4
IntEnz Enzyme Link: IntEnz 6.3.2.4
MEDLINE Enzyme Link: MEDLINE 6.3.2.4

EC number:6.3.2.4

MSA:

6.3.2.4;
Phylogenetic Tree:

6.3.2.4;
Uniprot:
M-CSA:
RHEA:11224 ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[OH;+0:6].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[O;H0;+0:11]-[*:12]>>[*:1]-[NH;+0:2]-[C;H0;+0:4](=[*:3])-[*:5].[*:12]-[OH;+0:11].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction