EC number:6.3.2.42

Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.2 Acid-D-amino-acid ligases (peptide synthases)
ID:6.3.2.42
Description:N-acetylaspartylglutamylglutamate synthase.
Alternative Name: NAAGS-II.
NAAG synthetase II.
N-acetylaspartylglutamylglutamate synthetase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.2.42
BRENDA Enzyme Link: BRENDA 6.3.2.42
KEGG Enzyme Link: KEGG6.3.2.42
BioCyc Enzyme Link: BioCyc 6.3.2.42
ExPASy Enzyme Link: ExPASy6.3.2.42
EC2PDB Enzyme Link: EC2PDB 6.3.2.42
ExplorEnz Enzyme Link: ExplorEnz 6.3.2.42
PRIAM enzyme-specific profiles Link: PRIAM 6.3.2.42
IntEnz Enzyme Link: IntEnz 6.3.2.42
MEDLINE Enzyme Link: MEDLINE 6.3.2.42

EC number:6.3.2.42

MSA:

6.3.2.42;
Phylogenetic Tree:

6.3.2.42;
Uniprot:
M-CSA:
RHEA:40039 2 ATP + 2 L-glutamate + N-acetyl-L-aspartate = 2 ADP + 2 H(+) + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate + 2 phosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:4].[*:5]-[NH2;+0:6].[*:7]=[C;H0;+0:8](-[OH;+0:9])-[*:10]-[NH2;+0:11].[*:12]=[P;H0;+0:13](-[*:14])(-[*:15])-[O;H0;+0:16]-[*:17].[*:18]=[P;H0;+0:19](-[*:20])(-[*:21])-[O;H0;+0:22]-[*:23]>>[*:1]-[C;H0;+0:2](=[*:3])-[NH;+0:11]-[*:10]-[C;H0;+0:8](=[*:7])-[NH;+0:6]-[*:5].[*:17]-[OH;+0:16].[*:23]-[OH;+0:22].[*:12]=[P;H0;+0:13](-[*:14])(-[*:15])-[OH;+0:4].[*:18]=[P;H0;+0:19](-[*:20])(-[*:21])-[OH;+0:9]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
N-acetylaspartylglutamate synthetase II synthesizes N-acetylaspartylglutamylglutamate.Lodder-Gadaczek J, Becker I, Gieselmann V, Wang-Eckhardt L, Eckhardt M2011 May 1321454531