EC number:6.3.2.44

Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.2 Acid-D-amino-acid ligases (peptide synthases)
ID:6.3.2.44
Description:Pantoate--beta-alanine ligase (ADP-forming).
Alternative Name: Pantothenate synthetase.
Pantoate--beta-alanine ligase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.2.44
BRENDA Enzyme Link: BRENDA 6.3.2.44
KEGG Enzyme Link: KEGG6.3.2.44
BioCyc Enzyme Link: BioCyc 6.3.2.44
ExPASy Enzyme Link: ExPASy6.3.2.44
EC2PDB Enzyme Link: EC2PDB 6.3.2.44
ExplorEnz Enzyme Link: ExplorEnz 6.3.2.44
PRIAM enzyme-specific profiles Link: PRIAM 6.3.2.44
IntEnz Enzyme Link: IntEnz 6.3.2.44
MEDLINE Enzyme Link: MEDLINE 6.3.2.44

EC number:6.3.2.44

MSA:

6.3.2.44;
Phylogenetic Tree:

6.3.2.44;
Uniprot:
M-CSA:
RHEA:27590 (R)-pantoate + ATP + beta-alanine = (R)-pantothenate + ADP + H(+) + phosphate
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[OH;+0:6].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[O;H0;+0:11]-[*:12]>>[*:12]-[OH;+0:11].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A novel isoform of pantothenate synthetase in the Archaea.Ronconi S, Jonczyk R, Genschel U2008 Jun18422645