| EC Tree |
| 6. Ligases |
| 6.3 Forming carbon-nitrogen bonds |
| 6.3.2 Acid-D-amino-acid ligases (peptide synthases) |
| ID: | 6.3.2.52 |
|---|---|
| Description: | Jasmonoyl--L-amino acid synthetase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 6.3.2.52 |
| BRENDA Enzyme Link: | BRENDA 6.3.2.52 |
| KEGG Enzyme Link: | KEGG6.3.2.52 |
| BioCyc Enzyme Link: | BioCyc 6.3.2.52 |
| ExPASy Enzyme Link: | ExPASy6.3.2.52 |
| EC2PDB Enzyme Link: | EC2PDB 6.3.2.52 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.3.2.52 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.3.2.52 |
| IntEnz Enzyme Link: | IntEnz 6.3.2.52 |
| MEDLINE Enzyme Link: | MEDLINE 6.3.2.52 |
| RHEA:55772 | a jasmonate + an L-alpha-amino acid + ATP = a jasmonyl-L-amino acid + AMP + diphosphate + H(+) |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]-[O;H0;+0:4]-[P;H0;+0:5](-[*:6])(=[*:7])-[*:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:3]-[OH;+0:4].[*:6]-[P;H0;+0:5](=[*:7])(-[*:8])-[OH;+0:12].[*:9]=[C;H0;+0:10](-[*:11])-[NH;+0:2]-[*:1] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The role of JAR1 in Jasmonoyl-L: -isoleucine production during Arabidopsis wound response. | Suza WP, Staswick PE | 2008 May | 18247047 |
| Substrate specificity and products of side-reactions catalyzed by jasmonate:amino acid synthetase (JAR1). | Guranowski A, Miersch O, Staswick PE, Suza W, Wasternack C | 2007 Mar 6 | 17291501 |
| Independently silencing two JAR family members impairs levels of trypsin proteinase inhibitors but not nicotine. | Wang L, Halitschke R, Kang JH, Berg A, Harnisch F, Baldwin IT | 2007 Jun | 17273867 |
| Silencing threonine deaminase and JAR4 in Nicotiana attenuata impairs jasmonic acid-isoleucine-mediated defenses against Manduca sexta. | Kang JH, Wang L, Giri A, Baldwin IT | 2006 Nov | 17085687 |
| The oxylipin signal jasmonic acid is activated by an enzyme that conjugates it to isoleucine in Arabidopsis. | Staswick PE, Tiryaki I | 2004 Aug | 15258265 |