Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.2 Acid-D-amino-acid ligases (peptide synthases)
ID:6.3.2.52
Description:Jasmonoyl--L-amino acid synthetase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.2.52
BRENDA Enzyme Link: BRENDA 6.3.2.52
KEGG Enzyme Link: KEGG6.3.2.52
BioCyc Enzyme Link: BioCyc 6.3.2.52
ExPASy Enzyme Link: ExPASy6.3.2.52
EC2PDB Enzyme Link: EC2PDB 6.3.2.52
ExplorEnz Enzyme Link: ExplorEnz 6.3.2.52
PRIAM enzyme-specific profiles Link: PRIAM 6.3.2.52
IntEnz Enzyme Link: IntEnz 6.3.2.52
MEDLINE Enzyme Link: MEDLINE 6.3.2.52
MSA:

6.3.2.52;

Phylogenetic Tree:

6.3.2.52;

Uniprot:
M-CSA:
RHEA:55772 a jasmonate + an L-alpha-amino acid + ATP = a jasmonyl-L-amino acid + AMP + diphosphate + H(+)
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[O;H0;+0:4]-[P;H0;+0:5](-[*:6])(=[*:7])-[*:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:3]-[OH;+0:4].[*:6]-[P;H0;+0:5](=[*:7])(-[*:8])-[OH;+0:12].[*:9]=[C;H0;+0:10](-[*:11])-[NH;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The role of JAR1 in Jasmonoyl-L: -isoleucine production during Arabidopsis wound response.Suza WP, Staswick PE2008 May18247047
Substrate specificity and products of side-reactions catalyzed by jasmonate:amino acid synthetase (JAR1).Guranowski A, Miersch O, Staswick PE, Suza W, Wasternack C2007 Mar 617291501
Independently silencing two JAR family members impairs levels of trypsin proteinase inhibitors but not nicotine.Wang L, Halitschke R, Kang JH, Berg A, Harnisch F, Baldwin IT2007 Jun17273867
Silencing threonine deaminase and JAR4 in Nicotiana attenuata impairs jasmonic acid-isoleucine-mediated defenses against Manduca sexta.Kang JH, Wang L, Giri A, Baldwin IT2006 Nov17085687
The oxylipin signal jasmonic acid is activated by an enzyme that conjugates it to isoleucine in Arabidopsis.Staswick PE, Tiryaki I2004 Aug15258265