EC number:6.3.3.5
| ID: | 6.3.3.5 |
|---|---|
| Description: | O-ureido-D-serine cyclo-ligase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.3.3.5 |
| BRENDA Enzyme Link: | BRENDA 6.3.3.5 |
| KEGG Enzyme Link: | KEGG6.3.3.5 |
| BioCyc Enzyme Link: | BioCyc 6.3.3.5 |
| ExPASy Enzyme Link: | ExPASy6.3.3.5 |
| EC2PDB Enzyme Link: | EC2PDB 6.3.3.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.3.3.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.3.3.5 |
| IntEnz Enzyme Link: | IntEnz 6.3.3.5 |
| MEDLINE Enzyme Link: | MEDLINE 6.3.3.5 |
| RHEA:36711 | ATP + H(+) + H2O + O-ureido-D-serine = ADP + CO2 + D-cycloserine + NH4(+) + phosphate |
| RULE(radius=1) | ([*:1]-[CH;+0:2](-[*:3])-[C;H0;+0:4](=[*:5])-[OH;+0:6].[*:7]=[C;H0;+0:8](-[*:9])-[NH2;+0:10]).[*:11]=[P;H0;+0:12](-[*:13])(-[*:14])-[O;H0;+0:15]-[*:16].[H+;H0:17].[OH2;+0:18]>>[*:16]-[OH;+0:15].[*:7]=[C;H0;+0:8](-[*:9])-[CH;+0:2](-[*:1])-[*:3].[*:5]=[C;H0;+0:4]=[O;H0;+0:6].[*:11]=[P;H0;+0:12](-[*:13])(-[*:14])-[OH;+0:18].[NH3;+0:10] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Establishment of an in vitro D-cycloserine-synthesizing system by using O-ureido-L-serine synthase and D-cycloserine synthetase found in the biosynthetic pathway. | Uda N, Matoba Y, Kumagai T, Oda K, Noda M, Sugiyama M | 2013 Jun | 23529730 |
| Molecular cloning and heterologous expression of a biosynthetic gene cluster for the antitubercular agent D-cycloserine produced by Streptomyces lavendulae. | Kumagai T, Koyama Y, Oda K, Noda M, Matoba Y, Sugiyama M | 2010 Mar | 20086163 |