EC number:6.3.4.12
Enzyme
Download| EC Tree |
| 6. Ligases |
| 6.3 Forming carbon-nitrogen bonds |
| 6.3.4 Other carbon-nitrogen ligases |
| ID: | 6.3.4.12 |
|---|---|
| Description: | Glutamate--methylamine ligase. |
| Alternative Name: |
Gamma-glutamylmethylamide synthetase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 6.3.4.12 |
| BRENDA Enzyme Link: | BRENDA 6.3.4.12 |
| KEGG Enzyme Link: | KEGG6.3.4.12 |
| BioCyc Enzyme Link: | BioCyc 6.3.4.12 |
| ExPASy Enzyme Link: | ExPASy6.3.4.12 |
| EC2PDB Enzyme Link: | EC2PDB 6.3.4.12 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.3.4.12 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.3.4.12 |
| IntEnz Enzyme Link: | IntEnz 6.3.4.12 |
| MEDLINE Enzyme Link: | MEDLINE 6.3.4.12 |
| RHEA:17117 | ATP + L-glutamate + methylamine = ADP + H(+) + N(5)-methyl-L-glutamine + phosphate |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[OH;+0:6].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[O;H0;+0:11]-[*:12]>>[*:12]-[OH;+0:11].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Gamma-glutamylmethylamide. A new intermediate in the metabolism of methylamine. | Kung HF, Wagner C | 1969 Aug 10 | 5800436 |
| Genetics of the glutamate-mediated methylamine utilization pathway in the facultative methylotrophic beta-proteobacterium Methyloversatilis universalis FAM5. | Latypova E, Yang S, Wang YS, Wang T, Chavkin TA, Hackett M, Schäfer H, Kalyuzhnaya MG | 2010 Jan | 19943898 |
| Cloning and expression of Methylovorus mays No. 9 gene encoding gamma-glutamylmethylamide synthetase: an enzyme usable in theanine formation by coupling with the alcoholic fermentation system of baker's yeast. | Yamamoto S, Wakayama M, Tachiki T | 2008 Jan | 18175924 |
| Characterization of theanine-forming enzyme from Methylovorus mays no. 9 in respect to utilization of theanine production. | Yamamoto S, Wakayama M, Tachiki T | 2007 Feb | 17284842 |