EC number:6.3.4.21

Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.4 Other carbon-nitrogen ligases
ID:6.3.4.21
Description:Nicotinate phosphoribosyltransferase.
Alternative Name: Nicotinic acid phosphoribosyltransferase.
Nicotinic acid mononucleotide pyrophosphorylase.
Nicotinic acid mononucleotide glycohydrolase.
Niacin ribonucleotidase.
Cath: 3.20.140.10; 3.20.20.70; 3.90.1170.20;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.4.21
BRENDA Enzyme Link: BRENDA 6.3.4.21
KEGG Enzyme Link: KEGG6.3.4.21
BioCyc Enzyme Link: BioCyc 6.3.4.21
ExPASy Enzyme Link: ExPASy6.3.4.21
EC2PDB Enzyme Link: EC2PDB 6.3.4.21
ExplorEnz Enzyme Link: ExplorEnz 6.3.4.21
PRIAM enzyme-specific profiles Link: PRIAM 6.3.4.21
IntEnz Enzyme Link: IntEnz 6.3.4.21
MEDLINE Enzyme Link: MEDLINE 6.3.4.21

EC number:6.3.4.21

MSA:

6.3.4.21;
Phylogenetic Tree:

6.3.4.21;
Uniprot:
M-CSA:
RHEA:36163 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[*:5].[*:6]:[n;H0;+0:7]:[*:8].[*:9]=[P;H0;+0:10](-[*:11])(-[*:12])-[O;H0;+0:13]-[*:14].[OH2;+0:15]>>[*:1]-[CH;+0:2](-[*:3])-[n+;H0:7](:[*:6]):[*:8].[*:14]-[OH;+0:13].[*:5]-[OH;+0:4].[*:9]=[P;H0;+0:10](-[*:11])(-[*:12])-[OH;+0:15]
Reaction
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References

TitleAuthorsDatePubMed ID
A new paradigm for biochemical energy coupling. Salmonella typhimurium nicotinate phosphoribosyltransferase.Vinitsky A, Grubmeyer C1993 Dec 57503993