| EC Tree |
| 6. Ligases |
| 6.3 Forming carbon-nitrogen bonds |
| 6.3.4 Other carbon-nitrogen ligases |
| ID: | 6.3.4.24 |
|---|---|
| Description: | Tyramine--L-glutamate ligase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 6.3.4.24 |
| BRENDA Enzyme Link: | BRENDA 6.3.4.24 |
| KEGG Enzyme Link: | KEGG6.3.4.24 |
| BioCyc Enzyme Link: | BioCyc 6.3.4.24 |
| ExPASy Enzyme Link: | ExPASy6.3.4.24 |
| EC2PDB Enzyme Link: | EC2PDB 6.3.4.24 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.3.4.24 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.3.4.24 |
| IntEnz Enzyme Link: | IntEnz 6.3.4.24 |
| MEDLINE Enzyme Link: | MEDLINE 6.3.4.24 |
| RHEA:43544 | ATP + L-glutamate + tyramine = ADP + gamma-L-glutamyltyramine + H(+) + phosphate |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[OH;+0:6].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[O;H0;+0:11]-[*:12]>>[*:12]-[OH;+0:11].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[OH;+0:6] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification and characterization of a tyramine-glutamate ligase (MfnD) involved in methanofuran biosynthesis. | Wang Y, Xu H, Harich KC, White RH | 2014 Oct 7 | 25211225 |