EC number:6.3.4.6
Enzyme
Download| EC Tree |
| 6. Ligases |
| 6.3 Forming carbon-nitrogen bonds |
| 6.3.4 Other carbon-nitrogen ligases |
3D structure
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| PDB |
1KEE;
1CS0;
1C3O;
1C30;
1A9X;
1M6V;
1W96;
1W93;
1CE8;
1BXR;
1JDB;
5CSL;
5CSK;
4HR7;
2GPW;
3RV3;
3RUP;
3JZI;
3JZF;
3G8D;
3G8C;
2W71;
2W70;
2W6Z;
2W6Q;
2W6P;
2W6O;
2W6N;
2W6M;
2VR1;
2V5A;
2V59;
2V58;
2J9G;
2GPS;
1DV2;
1DV1;
1BNC;
3RV4;
6G2D;
5KKN;
5DOU;
5DOT;
4RZQ;
4MV9;
4MV8;
4MV7;
4MV6;
4MV4;
4MV3;
4MV1;
4HQ6;
3JRX;
3JRW;
3GLK;
3GID;
2YL2;
2VQD;
2HJW;
2CQY;
2C00;
1T36;
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References
External Links
| UniProtKB Enzyme Link: | UniProtKB 6.3.4.6 |
| BRENDA Enzyme Link: | BRENDA 6.3.4.6 |
| KEGG Enzyme Link: | KEGG6.3.4.6 |
| BioCyc Enzyme Link: | BioCyc 6.3.4.6 |
| ExPASy Enzyme Link: | ExPASy6.3.4.6 |
| EC2PDB Enzyme Link: | EC2PDB 6.3.4.6 |
| ExplorEnz Enzyme Link: | ExplorEnz 6.3.4.6 |
| PRIAM enzyme-specific profiles Link: | PRIAM 6.3.4.6 |
| IntEnz Enzyme Link: | IntEnz 6.3.4.6 |
| MEDLINE Enzyme Link: | MEDLINE 6.3.4.6 |
| RHEA:20896 | ATP + hydrogencarbonate + urea = ADP + H(+) + phosphate + urea-1-carboxylate |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[OH;+0:6].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[O;H0;+0:11]-[*:12]>>[*:12]-[OH;+0:11].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1].[*:7]=[P;H0;+0:8](-[*:9])(-[*:10])-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Urea carboxylase and allophanate hydrolase are components of a multifunctional protein in yeast. | Sumrada RA, Cooper TG | 1982 Aug 10 | 6124544 |
| A second pathway to degrade pyrimidine nucleic acid precursors in eukaryotes. | Andersen G, Björnberg O, Polakova S, Pynyaha Y, Rasmussen A, Møller K, Hofer A, Moritz T, Sandrini MP, Merico AM, Compagno C, Akerlund HE, Gojković Z, Piskur J | 2008 Jul 18 | 18550080 |
| Enzymatic characterization of a prokaryotic urea carboxylase. | Kanamori T, Kanou N, Atomi H, Imanaka T | 2004 May | 15090492 |