EC number:6.3.4.7

Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.4 Other carbon-nitrogen ligases
ID:6.3.4.7
Description:Ribose-5-phosphate--ammonia ligase.
Alternative Name: Ribose 5-phosphate aminotransferase.
5-phosphoribosylamine synthetase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.4.7
BRENDA Enzyme Link: BRENDA 6.3.4.7
KEGG Enzyme Link: KEGG6.3.4.7
BioCyc Enzyme Link: BioCyc 6.3.4.7
ExPASy Enzyme Link: ExPASy6.3.4.7
EC2PDB Enzyme Link: EC2PDB 6.3.4.7
ExplorEnz Enzyme Link: ExplorEnz 6.3.4.7
PRIAM enzyme-specific profiles Link: PRIAM 6.3.4.7
IntEnz Enzyme Link: IntEnz 6.3.4.7
MEDLINE Enzyme Link: MEDLINE 6.3.4.7

EC number:6.3.4.7

MSA:

6.3.4.7;
Phylogenetic Tree:

6.3.4.7;
Uniprot:
M-CSA:
RHEA:13777 ATP + D-ribose 5-phosphate + NH4(+) = 5-phospho-D-ribosylamine + ADP + H(+) + phosphate
RULE(radius=1) [*:1]-[CH;+0:2](-[OH;+0:3])-[*:4]-[*:5]-[CH;+0:6]=[O;H0;+0:7].[*:8]=[P;H0;+0:9](-[*:10])(-[*:11])-[O;H0;+0:12]-[*:13].[NH3;+0:14]>>[*:1]-[CH;+0:2]1-[*:4]-[*:5]-[CH;+0:6](-[NH2;+0:14])-[O;H0;+0:7]-1.[*:13]-[OH;+0:12].[*:8]=[P;H0;+0:9](-[*:10])(-[*:11])-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Enzymatic synthesis of 5'-phosphoribosylamine from ribose 5-phosphate and ammonia, an alternate first step in purine biosynthesis.Reem GH1968 Nov 105699059