EC number:6.3.4.8

Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.4 Other carbon-nitrogen ligases
ID:6.3.4.8
Description:Imidazoleacetate--phosphoribosyldiphosphate ligase.
Alternative Name: 5-phosphoribosylimidazoleacetate synthetase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.4.8
BRENDA Enzyme Link: BRENDA 6.3.4.8
KEGG Enzyme Link: KEGG6.3.4.8
BioCyc Enzyme Link: BioCyc 6.3.4.8
ExPASy Enzyme Link: ExPASy6.3.4.8
EC2PDB Enzyme Link: EC2PDB 6.3.4.8
ExplorEnz Enzyme Link: ExplorEnz 6.3.4.8
PRIAM enzyme-specific profiles Link: PRIAM 6.3.4.8
IntEnz Enzyme Link: IntEnz 6.3.4.8
MEDLINE Enzyme Link: MEDLINE 6.3.4.8

EC number:6.3.4.8

MSA:

6.3.4.8;
Phylogenetic Tree:

6.3.4.8;
Uniprot:
M-CSA:
RHEA:16485 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazole-4-acetate = 1-(5-phosphoribosyl)imidazole-4-acetate + ADP + diphosphate + H(+) + phosphate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[*:5].[*:6]:[nH;+0:7]:[*:8].[*:9]=[P;H0;+0:10](-[*:11])(-[*:12])-[O;H0;+0:13]-[*:14].[OH2;+0:15]>>[*:1]-[CH;+0:2](-[*:3])-[n;H0;+0:7](:[*:6]):[*:8].[*:14]-[OH;+0:13].[*:5]-[OH;+0:4].[*:9]=[P;H0;+0:10](-[*:11])(-[*:12])-[OH;+0:15]
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References

TitleAuthorsDatePubMed ID
THE ENZYMATIC SYNTHESIS OF 5'-PHOSPHORIBOSYLIMIDAZOLEACETIC ACID.CROWLEY GM1964 Aug14235540