EC number:6.3.5.12

Enzyme

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     6. Ligases
        6.3 Forming carbon-nitrogen bonds
            6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
ID:6.3.5.12
Description:Ni-sirohydrochlorin a,c-diamide synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 6.3.5.12
BRENDA Enzyme Link: BRENDA 6.3.5.12
KEGG Enzyme Link: KEGG6.3.5.12
BioCyc Enzyme Link: BioCyc 6.3.5.12
ExPASy Enzyme Link: ExPASy6.3.5.12
EC2PDB Enzyme Link: EC2PDB 6.3.5.12
ExplorEnz Enzyme Link: ExplorEnz 6.3.5.12
PRIAM enzyme-specific profiles Link: PRIAM 6.3.5.12
IntEnz Enzyme Link: IntEnz 6.3.5.12
MEDLINE Enzyme Link: MEDLINE 6.3.5.12

EC number:6.3.5.12

MSA:

6.3.5.12;
Phylogenetic Tree:

6.3.5.12;
Uniprot:
M-CSA:
RHEA:52896 2 ATP + 2 H2O + 2 L-glutamine + Ni-sirohydrochlorin = 2 ADP + 2 H(+) + 2 L-glutamate + Ni-sirohydrochlorin a,c-diamide + 2 phosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[NH2;+0:4].[*:5]-[C;H0;+0:6](=[*:7])-[NH2;+0:8].([*:9]-[C;H0;+0:10](=[*:11])-[OH;+0:12].[*:13]-[C;H0;+0:14](=[*:15])-[OH;+0:16]).[*:17]-[O;H0;+0:18]-[P;H0;+0:19](=[*:20])(-[*:21])-[*:22].[*:23]=[P;H0;+0:24](-[*:25])(-[*:26])-[O;H0;+0:27]-[*:28].[OH2;+0:29].[OH2;+0:30]>>([*:9]-[C;H0;+0:10](=[*:11])-[NH2;+0:4].[*:13]-[C;H0;+0:14](=[*:15])-[NH2;+0:8]).[*:5]-[C;H0;+0:6](=[*:7])-[OH;+0:30].[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:29].[*:28]-[OH;+0:27].[*:17]-[OH;+0:18].[*:23]=[P;H0;+0:24](-[*:25])(-[*:26])-[OH;+0:12].[*:20]=[P;H0;+0:19](-[*:21])(-[*:22])-[OH;+0:16]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The biosynthetic pathway of coenzyme F430 in methanogenic and methanotrophic archaea.Zheng K, Ngo PD, Owens VL, Yang XP, Mansoorabadi SO2016 Oct 2127846569