Enzyme

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     6. Ligases
        6.4 Forming carbon-carbon bonds
            6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
ID:6.4.1.7
Description:2-oxoglutarate carboxylase.
Alternative Name: Oxalosuccinate synthetase.
OGC.
CFI.
Carboxylating factor for ICDH.
Prosite: PDOC50975; PDOC00676;
PDB:
PDBScop
Cath: 3.30.1490.20; 3.30.470.20; 3.40.50.20;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 6.4.1.7
BRENDA Enzyme Link: BRENDA 6.4.1.7
KEGG Enzyme Link: KEGG6.4.1.7
BioCyc Enzyme Link: BioCyc 6.4.1.7
ExPASy Enzyme Link: ExPASy6.4.1.7
EC2PDB Enzyme Link: EC2PDB 6.4.1.7
ExplorEnz Enzyme Link: ExplorEnz 6.4.1.7
PRIAM enzyme-specific profiles Link: PRIAM 6.4.1.7
IntEnz Enzyme Link: IntEnz 6.4.1.7
MEDLINE Enzyme Link: MEDLINE 6.4.1.7
MSA:

6.4.1.7;

Phylogenetic Tree:

6.4.1.7;

Uniprot:
M-CSA:
RHEA:20425 2-oxoglutarate + ATP + hydrogencarbonate = ADP + H(+) + oxalosuccinate + phosphate
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[*:4]=[C;H0;+0:5](-[*:6])-[OH;+0:7].[*:8]=[P;H0;+0:9](-[*:10])(-[*:11])-[O;H0;+0:12]-[*:13]>>[*:1]-[CH;+0:2](-[*:3])-[C;H0;+0:5](=[*:4])-[*:6].[*:13]-[OH;+0:12].[*:8]=[P;H0;+0:9](-[*:10])(-[*:11])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction