Enzyme

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EC Tree
     7. Translocases
        7.1 Catalysing the translocation of hydrons
            7.1.2 Linked to the hydrolysis of a nucleoside triphosphate
ID:7.1.2.1
Description:P-type H(+)-exporting transporter.
Alternative Name: Proton-translocating P-type ATPase.
Proton transport ATPase.
H(+)-transporting ATPase.
Prosite: PDOC00139;
PDB:
PDBScop

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 7.1.2.1
BRENDA Enzyme Link: BRENDA 7.1.2.1
KEGG Enzyme Link: KEGG7.1.2.1
BioCyc Enzyme Link: BioCyc 7.1.2.1
ExPASy Enzyme Link: ExPASy7.1.2.1
EC2PDB Enzyme Link: EC2PDB 7.1.2.1
ExplorEnz Enzyme Link: ExplorEnz 7.1.2.1
PRIAM enzyme-specific profiles Link: PRIAM 7.1.2.1
IntEnz Enzyme Link: IntEnz 7.1.2.1
MEDLINE Enzyme Link: MEDLINE 7.1.2.1
MSA:

7.1.2.1;

Phylogenetic Tree:

7.1.2.1;

Uniprot:
M-CSA:
RHEA:20852 ATP + H(+)(in) + H2O = ADP + 2 H(+)(out) + phosphate
RULE(radius=1) [*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[OH2;+0:7]>>[*:6]-[OH;+0:5].[*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Metabolic modulation of transport coupling ratio in yeast plasma membrane H(+)-ATPase.Venema K, Palmgren MG1995 Aug 187642655
The proton-translocating ATPase of the fungal plasma membrane.Goffeau A, Slayman CW1981 Dec 306461354
Yeast plasma membrane ATPase is essential for growth and has homology with (Na+ + K+), K+- and Ca2+-ATPases.Serrano R, Kielland-Brandt MC, Fink GR1986 Feb 20-263005867
H+/ATP stoichiometry of proton pumps from Neurospora crassa and Escherichia coli.Perlin DS, San Francisco MJ, Slayman CW, Rosen BP1986 Jul2425739
Catalytic and regulatory sites of yeast plasma membrane H(+)-ATPase studied by directed mutagenesis.Serrano R, Portillo F1990 Jul 252144186