EC number:7.2.2.13
Enzyme
Download| EC Tree |
| 7. Translocases |
| 7.2 Catalysing the translocation of inorganic cations |
| 7.2.2 Linked to the hydrolysis of a nucleoside triphosphate |
| ID: | 7.2.2.13 | ||||||||||||||||||||
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| Description: | Na(+)/K(+)-exchanging ATPase. | ||||||||||||||||||||
| Alternative Name: |
Sodium/potassium-transporting ATPase. Sodium pump. Na,K-activated ATPase. Na(+)/K(+)-ATPase. | ||||||||||||||||||||
| Prosite: | PDOC00328; PDOC00139; | ||||||||||||||||||||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 7.2.2.13 |
| BRENDA Enzyme Link: | BRENDA 7.2.2.13 |
| KEGG Enzyme Link: | KEGG7.2.2.13 |
| BioCyc Enzyme Link: | BioCyc 7.2.2.13 |
| ExPASy Enzyme Link: | ExPASy7.2.2.13 |
| EC2PDB Enzyme Link: | EC2PDB 7.2.2.13 |
| ExplorEnz Enzyme Link: | ExplorEnz 7.2.2.13 |
| PRIAM enzyme-specific profiles Link: | PRIAM 7.2.2.13 |
| IntEnz Enzyme Link: | IntEnz 7.2.2.13 |
| MEDLINE Enzyme Link: | MEDLINE 7.2.2.13 |
| RHEA:18353 | ATP + H2O + K(+)(out) + Na(+)(in) = ADP + H(+) + K(+)(in) + Na(+)(out) + phosphate |
| RULE(radius=1) | [*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[OH2;+0:7]>>[*:6]-[OH;+0:5].[*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The Na,K-ATPase. | Skou JC, Esmann M | 1992 Jun | 1328174 |
| Structure-function relationships of Na(+), K(+), ATP, or Mg(2+) binding and energy transduction in Na,K-ATPase. | Jorgensen PL, Pedersen PA | 2001 May 1 | 11248189 |