EC number:7.2.2.3
Enzyme
Download| EC Tree |
| 7. Translocases |
| 7.2 Catalysing the translocation of inorganic cations |
| 7.2.2 Linked to the hydrolysis of a nucleoside triphosphate |
| ID: | 7.2.2.3 | ||
|---|---|---|---|
| Description: | P-type Na(+) transporter. | ||
| Alternative Name: |
Sodium-translocating P-type ATPase. Sodium-exporting ATPase. Sodium transport ATPase. Na(+)-transporting ATPase. Na(+)-exporting ATPase. | ||
| Prosite: | PDOC00139; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 7.2.2.3 |
| BRENDA Enzyme Link: | BRENDA 7.2.2.3 |
| KEGG Enzyme Link: | KEGG7.2.2.3 |
| BioCyc Enzyme Link: | BioCyc 7.2.2.3 |
| ExPASy Enzyme Link: | ExPASy7.2.2.3 |
| EC2PDB Enzyme Link: | EC2PDB 7.2.2.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 7.2.2.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 7.2.2.3 |
| IntEnz Enzyme Link: | IntEnz 7.2.2.3 |
| MEDLINE Enzyme Link: | MEDLINE 7.2.2.3 |
| RHEA:14633 | ATP + H2O + Na(+)(in) = ADP + H(+) + Na(+)(out) + phosphate |
| RULE(radius=1) | [*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[OH2;+0:7]>>[*:6]-[OH;+0:5].[*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Overexpression of the sodium ATPase of Saccharomyces cerevisiae: conditions for phosphorylation from ATP and Pi. | Benito B, Quintero FJ, Rodríguez-Navarro A | 1997 Sep 4 | 9315618 |
| The complete inventory of the yeast Saccharomyces cerevisiae P-type transport ATPases. | Catty P, de Kerchove d'Exaerde A, Goffeau A | 1997 Jun 16 | 9224683 |
| A two-gene ABC-type transport system that extrudes Na+ in Bacillus subtilis is induced by ethanol or protonophore. | Cheng J, Guffanti AA, Krulwich TA | 1997 Mar | 9106203 |
| The PMR2 gene cluster encodes functionally distinct isoforms of a putative Na+ pump in the yeast plasma membrane. | Wieland J, Nitsche AM, Strayle J, Steiner H, Rudolph HK | 1995 Aug 15 | 7664728 |
| The Bacillus subtilis NatK-NatR two-component system regulates expression of the natAB operon encoding an ABC transporter for sodium ion extrusion. | Ogura M, Tsukahara K, Hayashi K, Tanaka T | 2007 Mar | 17322186 |