EC number:7.2.2.9
Enzyme
Download| EC Tree |
| 7. Translocases |
| 7.2 Catalysing the translocation of inorganic cations |
| 7.2.2 Linked to the hydrolysis of a nucleoside triphosphate |
| ID: | 7.2.2.9 | ||
|---|---|---|---|
| Description: | P-type Cu(2+) transporter. | ||
| Alternative Name: |
Cu(2+)-exporting ATPase. | ||
| Prosite: | PDOC00139; | ||
| PDB: |
|
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 7.2.2.9 |
| BRENDA Enzyme Link: | BRENDA 7.2.2.9 |
| KEGG Enzyme Link: | KEGG7.2.2.9 |
| BioCyc Enzyme Link: | BioCyc 7.2.2.9 |
| ExPASy Enzyme Link: | ExPASy7.2.2.9 |
| EC2PDB Enzyme Link: | EC2PDB 7.2.2.9 |
| ExplorEnz Enzyme Link: | ExplorEnz 7.2.2.9 |
| PRIAM enzyme-specific profiles Link: | PRIAM 7.2.2.9 |
| IntEnz Enzyme Link: | IntEnz 7.2.2.9 |
| MEDLINE Enzyme Link: | MEDLINE 7.2.2.9 |
| RHEA:10376 | ATP + Cu(2+)(in) + H2O = ADP + Cu(2+)(out) + H(+) + phosphate |
| RULE(radius=1) | [*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[OH2;+0:7]>>[*:6]-[OH;+0:5].[*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Conformations of the apo-, substrate-bound and phosphate-bound ATP-binding domain of the Cu(II) ATPase CopB illustrate coupling of domain movement to the catalytic cycle. | Jayakanthan S, Roberts SA, Weichsel A, Argüello JM, McEvoy MM | 2012 Oct | 22663904 |
| Archaeoglobus fulgidus CopB is a thermophilic Cu2+-ATPase: functional role of its histidine-rich-N-terminal metal binding domain. | Mana-Capelli S, Mandal AK, Argüello JM | 2003 Oct 17 | 12876283 |