EC number:7.2.4.3
Enzyme
Download| EC Tree |
| 7. Translocases |
| 7.2 Catalysing the translocation of inorganic cations |
| 7.2.4 Linked to decarboxylation |
| ID: | 7.2.4.3 |
|---|---|
| Description: | (S)-methylmalonyl-CoA decarboxylase (sodium-transporting). |
| Alternative Name: |
Methylmalonyl-coenzyme A decarboxylase. (S)-methylmalonyl-CoA carboxy-lyase. (S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 7.2.4.3 |
| BRENDA Enzyme Link: | BRENDA 7.2.4.3 |
| KEGG Enzyme Link: | KEGG7.2.4.3 |
| BioCyc Enzyme Link: | BioCyc 7.2.4.3 |
| ExPASy Enzyme Link: | ExPASy7.2.4.3 |
| EC2PDB Enzyme Link: | EC2PDB 7.2.4.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 7.2.4.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 7.2.4.3 |
| IntEnz Enzyme Link: | IntEnz 7.2.4.3 |
| MEDLINE Enzyme Link: | MEDLINE 7.2.4.3 |
| RHEA:21396 | (S)-methylmalonyl-CoA + H(+) = CO2 + propanoyl-CoA |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[*:6].[H+;H0:7]>>[*:5]-[CH2;+0:4]-[*:6].[*:1]=[C;H0;+0:2]=[O;H0;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Methylmalonyl-CoA decarboxylase from Propionigenium modestum--cloning and sequencing of the structural genes and purification of the enzyme complex. | Bott M, Pfister K, Burda P, Kalbermatter O, Woehlke G, Dimroth P | 1997 Dec 1 | 9428714 |
| Expression of the sodium ion pump methylmalonyl-coenzyme A-decarboxylase from Veillonella parvula and of mutated enzyme specimens in Escherichia coli. | Huder JB, Dimroth P | 1995 Jul | 7601825 |
| Conversion of the chemical energy of methylmalonyl-CoA decarboxylation into a Na+ gradient. | Hilpert W, Dimroth P | 1982 Apr 8 | 7070502 |
| Methylmalonyl coenzyme A decarboxylase. Its role in succinate decarboxylation by Micrococcus lactilyticus. | Galivan JH, Allen SH | 1968 Mar 25 | 5646172 |
| The carboxyltransferase activity of the sodium-ion-translocating methylmalonyl-CoA decarboxylase of Veillonella alcalescens. | Hoffmann A, Hilpert W, Dimroth P | 1989 Feb 15 | 2920730 |