EC number:1.1.98.3
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.98 With other, known, physiological acceptors |
| ID: | 1.1.98.3 |
|---|---|
| Description: | Decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase. |
| Alternative Name: |
Decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.98.3 |
| BRENDA Enzyme Link: | BRENDA 1.1.98.3 |
| KEGG Enzyme Link: | KEGG1.1.98.3 |
| BioCyc Enzyme Link: | BioCyc 1.1.98.3 |
| ExPASy Enzyme Link: | ExPASy1.1.98.3 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.98.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.98.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.98.3 |
| IntEnz Enzyme Link: | IntEnz 1.1.98.3 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.98.3 |
| RHEA:33899 | FAD + H(+) + trans,octa-cis-decaprenylphospho-beta-D-ribofuranose = FADH2 + trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]:[c;H0;+0:6]1:[n;H0;+0:7]:[*:8]:[*:9]:[n;H0;+0:10](-[*:11]):[c;H0;+0:12]-1:[n;H0;+0:13]:[*:14].[H+;H0:15]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]:[c;H0;+0:6]1:[c;H0;+0:12](:[nH;+0:13]:[*:14])-[N;H0;+0:10](-[*:11])-[*:9]:[*:8]-[NH;+0:7]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1. | Trefzer C, Škovierová H, Buroni S, Bobovská A, Nenci S, Molteni E, Pojer F, Pasca MR, Makarov V, Cole ST, Riccardi G, Mikušová K, Johnsson K | 2012 Jan 18 | 22188377 |
| Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis. | Ribeiro AL, Degiacomi G, Ewann F, Buroni S, Incandela ML, Chiarelli LR, Mori G, Kim J, Contreras-Dominguez M, Park YS, Han SJ, Brodin P, Valentini G, Rizzi M, Riccardi G, Pasca MR | 2011 | 22069462 |