EC number:2.3.1.230

Enzyme

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EC Tree
     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.230
Description:2-heptyl-4(1H)-quinolone synthase.
Cath: 3.40.47.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.230
BRENDA Enzyme Link: BRENDA 2.3.1.230
KEGG Enzyme Link: KEGG2.3.1.230
BioCyc Enzyme Link: BioCyc 2.3.1.230
ExPASy Enzyme Link: ExPASy2.3.1.230
EC2PDB Enzyme Link: EC2PDB 2.3.1.230
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.230
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.230
IntEnz Enzyme Link: IntEnz 2.3.1.230
MEDLINE Enzyme Link: MEDLINE 2.3.1.230

EC number:2.3.1.230

MSA:

2.3.1.230;
Phylogenetic Tree:

2.3.1.230;
Uniprot:
M-CSA:
RHEA:50396 (2-aminobenzoyl)acetate + H(+) + octanoyl-CoA = 2-heptyl-4-quinolone + CO2 + CoA + H2O
RULE(radius=1) [*:1]=[C;H0;+0:2](-[*:3]:[*:4]-[NH2;+0:5])-[CH2;+0:6]-[C;H0;+0:7](=[O;H0;+0:8])-[OH;+0:9].[*:10]=[C;H0;+0:11](-[CH2;+0:12]-[*:13])-[S;H0;+0:14]-[*:15].[H+;H0:16]>>[*:13]-[CH2;+0:12]-[c;H0;+0:7]1:[cH;+0:6]:[c;H0;+0:2](=[*:1]):[*:3]:[*:4]:[nH;+0:5]:1.[*:15]-[SH;+0:14].[*:10]=[C;H0;+0:11]=[O;H0;+0:8].[OH2;+0:9]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
The end of an old hypothesis: the pseudomonas signaling molecules 4-hydroxy-2-alkylquinolines derive from fatty acids, not 3-ketofatty acids.Dulcey CE, Dekimpe V, Fauvelle DA, Milot S, Groleau MC, Doucet N, Rahme LG, Lépine F, Déziel E2013 Dec 1924239007
PqsBC, a Condensing Enzyme in the Biosynthesis of the Pseudomonas aeruginosa Quinolone Signal: CRYSTAL STRUCTURE, INHIBITION, AND REACTION MECHANISM.Drees SL, Li C, Prasetya F, Saleem M, Dreveny I, Williams P, Hennecke U, Emsley J, Fetzner S2016 Mar 2526811339