Enzyme

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EC Tree
     5. Isomerases
        5.3 Intramolecular oxidoreductases
            5.3.3 Transposing C=C bonds
ID:5.3.3.5
Description:Cholestenol Delta-isomerase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 5.3.3.5
BRENDA Enzyme Link: BRENDA 5.3.3.5
KEGG Enzyme Link: KEGG5.3.3.5
BioCyc Enzyme Link: BioCyc 5.3.3.5
ExPASy Enzyme Link: ExPASy5.3.3.5
EC2PDB Enzyme Link: EC2PDB 5.3.3.5
ExplorEnz Enzyme Link: ExplorEnz 5.3.3.5
PRIAM enzyme-specific profiles Link: PRIAM 5.3.3.5
IntEnz Enzyme Link: IntEnz 5.3.3.5
MEDLINE Enzyme Link: MEDLINE 5.3.3.5
MSA:

5.3.3.5;

Phylogenetic Tree:

5.3.3.5;

Uniprot:
M-CSA:
RHEA:15281 5alpha-cholest-7-en-3beta-ol = 5alpha-cholest-8-en-3beta-ol
RULE(radius=1) [*:1]-[CH;+0:2]=[C;H0;+0:3](-[*:4])-[CH;+0:5](-[*:6])-[*:7]>>[*:1]-[CH2;+0:2]-[C;H0;+0:3](-[*:4])=[C;H0;+0:5](-[*:6])-[*:7]
Reaction
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References

TitleAuthorsDatePubMed ID
Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast.Silve S, Dupuy PH, Labit-Lebouteiller C, Kaghad M, Chalon P, Rahier A, Taton M, Lupker J, Shire D, Loison G1996 Sep 138798407
The reversibility of the delta8-cholestenol-delta7-cholestenol isomerase reaction in cholesterol biosynthesis.Wilton DC, Rahimtula AD, Akhtar M1969 Aug5810070
Purification, characterization and catalytic properties of human sterol 8-isomerase.Nes WD, Zhou W, Dennis AL, Li H, Jia Z, Keith RA, Piser TM, Furlong ST2002 Nov 112133002