ID: | 5.3.3.5 |
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Description: | Cholestenol Delta-isomerase. |
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BRENDA Enzyme Link: | BRENDA 5.3.3.5 |
KEGG Enzyme Link: | KEGG5.3.3.5 |
BioCyc Enzyme Link: | BioCyc 5.3.3.5 |
ExPASy Enzyme Link: | ExPASy5.3.3.5 |
EC2PDB Enzyme Link: | EC2PDB 5.3.3.5 |
ExplorEnz Enzyme Link: | ExplorEnz 5.3.3.5 |
PRIAM enzyme-specific profiles Link: | PRIAM 5.3.3.5 |
IntEnz Enzyme Link: | IntEnz 5.3.3.5 |
MEDLINE Enzyme Link: | MEDLINE 5.3.3.5 |
RHEA:15281 | 5alpha-cholest-7-en-3beta-ol = 5alpha-cholest-8-en-3beta-ol |
RULE(radius=1) | [*:1]-[CH;+0:2]=[C;H0;+0:3](-[*:4])-[CH;+0:5](-[*:6])-[*:7]>>[*:1]-[CH2;+0:2]-[C;H0;+0:3](-[*:4])=[C;H0;+0:5](-[*:6])-[*:7] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
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Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast. | Silve S, Dupuy PH, Labit-Lebouteiller C, Kaghad M, Chalon P, Rahier A, Taton M, Lupker J, Shire D, Loison G | 1996 Sep 13 | 8798407 |
The reversibility of the delta8-cholestenol-delta7-cholestenol isomerase reaction in cholesterol biosynthesis. | Wilton DC, Rahimtula AD, Akhtar M | 1969 Aug | 5810070 |
Purification, characterization and catalytic properties of human sterol 8-isomerase. | Nes WD, Zhou W, Dennis AL, Li H, Jia Z, Keith RA, Piser TM, Furlong ST | 2002 Nov 1 | 12133002 |